L-Tyrosine

Quick Facts

Form: L-Tyrosine (free form amino acid)

Dosage: 500 mg

Evidence Strength: Strong – Well studied in relation to cognition and performance under demanding conditions.

Time to Effect: Acute – typically felt within hours of supplementation.

L-Tyrosine is an amino acid that plays a role in supporting focus and cognitive performance in demanding situations. At Spyr, we include it for its role as a precursor to neurotransmitters such as dopamine and norepinephrine, helping maintain performance during mental or physical stress.

Benefits

Benefit Evidence Level Typical Dosage Notes
Supports mental focus during demanding or stressful situations. Moderate 300–500 mg per day L-Tyrosine is a precursor to dopamine and norepinephrine, neurotransmitters that help regulate attention and cognitive performance. Supplementation has been shown to support focus when the brain is under higher demand.
Contributes to maintaining cognitive function when under fatigue. Moderate 300–500 mg per day By replenishing neurotransmitter precursors, L-Tyrosine may help sustain working memory and problem-solving during periods of mental strain. Evidence is strongest in sleep deprivation and multitasking conditions.
Provides the building blocks for key neurotransmitters involved in performance. Strong 300–500 mg per day L-Tyrosine is directly converted into dopamine, norepinephrine, and epinephrine. These neurotransmitters play essential roles in focus, alertness, and stress adaptation, making Tyrosine a valuable daily support nutrient.
Plays a role in supporting the body’s response to physical and psychological stress. Moderate 300–500 mg per day As a building block for catecholamines, L-Tyrosine helps maintain neurotransmitter levels when demand is elevated. This may support resilience in both physical training and mentally demanding environments.
May help maintain mood and motivation by supporting dopamine production. Emerging 300–500 mg per day Research suggests that adequate dopamine levels are linked with motivation and mood stability. L-Tyrosine’s role as a precursor offers a potential supportive effect, though more studies are needed.
Evidence Level Moderate
Notes L-Tyrosine is a precursor to dopamine and norepinephrine, neurotransmitters that help regulate attention and cognitive performance. Supplementation has been shown to support focus when the brain is under higher demand.
Evidence Level Moderate
Notes By replenishing neurotransmitter precursors, L-Tyrosine may help sustain working memory and problem-solving during periods of mental strain. Evidence is strongest in sleep deprivation and multitasking conditions.
Evidence Level Strong
Notes L-Tyrosine is directly converted into dopamine, norepinephrine, and epinephrine. These neurotransmitters play essential roles in focus, alertness, and stress adaptation, making Tyrosine a valuable daily support nutrient.
Evidence Level Moderate
Notes As a building block for catecholamines, L-Tyrosine helps maintain neurotransmitter levels when demand is elevated. This may support resilience in both physical training and mentally demanding environments.
Evidence Level Emerging
Notes Research suggests that adequate dopamine levels are linked with motivation and mood stability. L-Tyrosine’s role as a precursor offers a potential supportive effect, though more studies are needed.

Mechanism

L-Tyrosine contributes to the production of neurotransmitters like dopamine and norepinephrine. These are involved in focus, attention, and stress response. Supplementation helps support performance when neurotransmitter demand is increased.

Forms & Timing

Spyr Rise provides 500 mg of L-Tyrosine per serve, included to support focus and performance in demanding conditions.

Included in Spyr Rise in its pure free-form, chosen for its proven ability to support cognitive function in stressful or high-demand conditions. Best taken in the morning or before periods of focus.

Safety

Consult a healthcare professional before use if you are pregnant, nursing, under 18, or have a medical condition.

L-Tyrosine is naturally present in many foods and well tolerated in supplemental form. It is widely regarded as safe at typical dietary levels.

Studies

Study Title Outcome Year Design Population Dosage Duration Study Type Takeaway
Cognitive performance and stress response after L-Tyrosine supplementation L-Tyrosine improved performance on cognitive tasks under acute stress compared with placebo. 1995 Randomized, double-blind, placebo-controlled trial Healthy adults under stress conditions Single dose ~150 mg/kg prior to testing Randomized controlled trial Shows L-Tyrosine can help preserve focus and performance when the brain is under pressure.
The effects of L-Tyrosine on cognitive performance during extended wakefulness Participants given L-Tyrosine showed better memory and cognitive function after sleep deprivation than placebo. 1995 Randomized, double-blind, placebo-controlled Healthy adults under 24-h sleep deprivation 150 mg/kg divided doses Randomized controlled trial Supports L-Tyrosine’s role in sustaining performance under fatigue.
Effect of L-Tyrosine supplementation on blood pressure and catecholamine response to cold exposure L-Tyrosine attenuated blood pressure increases and catecholamine depletion during cold stress. 1989 Controlled human study Healthy adults exposed to cold stress 150 mg/kg single dose Controlled trial Demonstrates L-Tyrosine’s role in supporting physiological stress response.
The effect of L-Tyrosine on mood during acute stress Supplementation was associated with improved mood states under stress compared with placebo. 1994 Randomized controlled trial Healthy adults under stress protocols 150 mg/kg oral dose Randomized controlled trial Emerging evidence links L-Tyrosine to maintaining positive mood and motivation under stress.
L-Tyrosine availability influences dopamine synthesis in humans Demonstrated that L-Tyrosine availability is rate-limiting for dopamine synthesis under demanding conditions. 1988 Mechanistic human neurochemical study Healthy human subjects with measured neurotransmitter response Acute supplementation protocol (per paper) Mechanistic study Provides biochemical rationale: L-Tyrosine fuels dopamine and norepinephrine production.
Cognitive performance and stress response after L-Tyrosine supplementation
Outcome L-Tyrosine improved performance on cognitive tasks under acute stress compared with placebo.
Year 1995
Design Randomized, double-blind, placebo-controlled trial
Population Healthy adults under stress conditions
Dosage Duration Single dose ~150 mg/kg prior to testing
Study Type Randomized controlled trial
Takeaway Shows L-Tyrosine can help preserve focus and performance when the brain is under pressure.
The effects of L-Tyrosine on cognitive performance during extended wakefulness
Outcome Participants given L-Tyrosine showed better memory and cognitive function after sleep deprivation than placebo.
Year 1995
Design Randomized, double-blind, placebo-controlled
Population Healthy adults under 24-h sleep deprivation
Dosage Duration 150 mg/kg divided doses
Study Type Randomized controlled trial
Takeaway Supports L-Tyrosine’s role in sustaining performance under fatigue.
Effect of L-Tyrosine supplementation on blood pressure and catecholamine response to cold exposure
Outcome L-Tyrosine attenuated blood pressure increases and catecholamine depletion during cold stress.
Year 1989
Design Controlled human study
Population Healthy adults exposed to cold stress
Dosage Duration 150 mg/kg single dose
Study Type Controlled trial
Takeaway Demonstrates L-Tyrosine’s role in supporting physiological stress response.
The effect of L-Tyrosine on mood during acute stress
Outcome Supplementation was associated with improved mood states under stress compared with placebo.
Year 1994
Design Randomized controlled trial
Population Healthy adults under stress protocols
Dosage Duration 150 mg/kg oral dose
Study Type Randomized controlled trial
Takeaway Emerging evidence links L-Tyrosine to maintaining positive mood and motivation under stress.
L-Tyrosine availability influences dopamine synthesis in humans
Outcome Demonstrated that L-Tyrosine availability is rate-limiting for dopamine synthesis under demanding conditions.
Year 1988
Design Mechanistic human neurochemical study
Population Healthy human subjects with measured neurotransmitter response
Dosage Duration Acute supplementation protocol (per paper)
Study Type Mechanistic study
Takeaway Provides biochemical rationale: L-Tyrosine fuels dopamine and norepinephrine production.

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Frequently Asked Questions

Question Answer
Why is L-Tyrosine included in Spyr Rise? L-Tyrosine is an amino acid used by the body to make neurotransmitters involved in focus and stress response.
How does L-Tyrosine support focus and performance? It supports the production of dopamine and norepinephrine, which are key to mental performance under demanding conditions.
When is the best time to take L-Tyrosine? Best used in the morning or before demanding work or training to support focus and alertness.
Is L-Tyrosine safe for daily use? Yes, L-Tyrosine is a non-essential amino acid found in many foods and safe at supplemental doses.
Answer L-Tyrosine is an amino acid used by the body to make neurotransmitters involved in focus and stress response.
Answer It supports the production of dopamine and norepinephrine, which are key to mental performance under demanding conditions.
Answer Best used in the morning or before demanding work or training to support focus and alertness.
Answer Yes, L-Tyrosine is a non-essential amino acid found in many foods and safe at supplemental doses.

Still curious?

If you still have any questions about L-Tyrosine, head on over to our contact page and fire away - our team will be happy to assist.

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